Comprehensive literature review and statistical considerations for microarray meta-analysis
نویسندگان
چکیده
منابع مشابه
Comprehensive literature review and statistical considerations for microarray meta-analysis
With the rapid advances of various high-throughput technologies, generation of '-omics' data is commonplace in almost every biomedical field. Effective data management and analytical approaches are essential to fully decipher the biological knowledge contained in the tremendous amount of experimental data. Meta-analysis, a set of statistical tools for combining multiple studies of a related hyp...
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Over the last decade, genome-wide association studies (GWAS) have become the standard tool for gene discovery in human disease research. While debate continues about how to get the most out of these studies and on occasion about how much value these studies really provide, it is clear that many of the strongest results have come from large-scale mega-consortia and/or meta-analyses that combine ...
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Acknowledgment: This work is supported by NIH NHLBI RO1 073087 to CKS. In addition, microarray related research in the laboratory is supported by NIH GM069589 and NS42617 to CKS. Correspondence: Professor Chandan K. Sen 512 Davis Heart & Lung Research Institute The Ohio State University Medical Center 473 W. 12 Avenue, Columbus, OH 43210 Tel. 614 247 7658; Fax 614 247 7818 [email protected]...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2012
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkr1265